Records of Natural Products

Records of Natural Products

1 Benzodiazepine Derivatives from Marine-Derived Streptomyces cacaoi 14CM034

Yazarlar: Semiha Çetinel Aksoy, Melis Küçüksolak, Ataç Uzel, Erdal Bedir

Cilt 15 , Sayı 6 , 2021 , Sayfalar 602-607

Konular:-

DOI:10.25135/rnp.203.20.08.1766

Anahtar Kelimeler:Marine actinobacterium,Streptomyces cacaoi,Benzodiazepine,Antimicrobial activity,Antibiotics

Özet: 7-methoxy-8-hydroxy cycloanthranilylproline (2), a new natural product with pyrrolobenzodiazepine (PBD) framework, was isolated from marine-derived actinobacterium Streptomyces cacaoi 14CM034, together with cycloanthranilylproline (1). Structural elucidation of the compounds was based on FTIR, 1D- (1H and 13C NMR), 2D-NMR (COSY, HMBC and NOESY) and HR-MS analyses. Compounds 1 and 2 exhibited notable antimicrobial activity. The presence of PBD derivatives in S. cacaoi was first demonstrated with this study.

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@article{2021, title={1 Benzodiazepine Derivatives from Marine-Derived Streptomyces cacaoi 14CM034}, volume={15}, number={602–607}, publisher={Records of Natural Products}, author={Semiha Çetinel Aksoy, Melis Küçüksolak, Ataç Uzel, Erdal Bedir}, year={2021} }
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Semiha Çetinel Aksoy, Melis Küçüksolak, Ataç Uzel, Erdal Bedir. (2021). 1 Benzodiazepine Derivatives from Marine-Derived Streptomyces cacaoi 14CM034 (Vol. 15). Vol. 15. Records of Natural Products.
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Semiha Çetinel Aksoy, Melis Küçüksolak, Ataç Uzel, Erdal Bedir. 1 Benzodiazepine Derivatives from Marine-Derived Streptomyces Cacaoi 14CM034. no. 602–607, Records of Natural Products, 2021.
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