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Records of Natural Products
Yazarlar: Fatma Tosun, Erdi C. Aytar, John A. Beutler, Jennifer A. Wilson, Mahmut Miski
Konular:-
DOI:10.25135/rnp.242.21.02.1990
Anahtar Kelimeler:Heptaptera cilicica,Apiaceae,Sesquiterpene coumarins,Cytotoxic activity
Özet: Preliminary 2-day cancer cell screening assays indicated that the dichloromethane extract of the roots of Heptaptera cilicica showed relatively strong cytotoxic activity. Eleven sesquiterpene coumarin ethers with potent and selective cytotoxic activities were isolated from the dichloromethane extract of the roots of H. cilicica. Furthermore, revised spectroscopic data for 14′-acetoxybadrakemone (4) and complete NMR spectroscopic assignments for colladonin (6) and colladin (7) are reported.