Records of Natural Products

Records of Natural Products

Three Isoflavonoid Glycosides from the Rhizomes of Achyranthes bidentata and their Protective Effects on H2O2 Induced H9c2 Cardiomyocytes Injury

Yazarlar: Yue Li, Jun Chi, Ping Wang, Lingxia Zhang, Qingxia Li, Qingmei Feng, Liping Dai, Zhimin Wang

Cilt 16 , Sayı 2 , 2022 , Sayfalar 110-117

Konular:-

DOI:10.25135/rnp.257.21.04.2039

Anahtar Kelimeler:Achyranthes bidentata,Isoflavonoid glycosides,Antioxidant activity

Özet: A new isoflavonoid glycoside, achyranthoside C (1), along with two known compounds (2 and 3) were isolated from the rhizomes of Achyranthes bidentata. Compounds 1-2 were two rare natural isoflavonoid glycosides with C8 hydroxymethylene derivatization. Their structures were elucidated through comprehensive 1D and 2D NMR, UV, IR, and HRMS analyses. Bioassay results showed all the three compounds had obviously cell-protective effects against H2O2-induced H9c2 cardiomyocytes injury in a concentration -dependent manner.

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@article{2022, title={ Three Isoflavonoid Glycosides from the Rhizomes of Achyranthes bidentata and their Protective Effects on H2O2 Induced H9c2 Cardiomyocytes Injury}, volume={16}, number={110–117}, publisher={Records of Natural Products}, author={Yue Li, Jun Chi, Ping Wang, Lingxia Zhang, Qingxia Li, Qingmei Feng, Liping Dai, Zhimin Wang}, year={2022} }
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Yue Li, Jun Chi, Ping Wang, Lingxia Zhang, Qingxia Li, Qingmei Feng, Liping Dai, Zhimin Wang. (2022). Three Isoflavonoid Glycosides from the Rhizomes of Achyranthes bidentata and their Protective Effects on H2O2 Induced H9c2 Cardiomyocytes Injury (Vol. 16). Vol. 16. Records of Natural Products.
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Yue Li, Jun Chi, Ping Wang, Lingxia Zhang, Qingxia Li, Qingmei Feng, Liping Dai, Zhimin Wang. Three Isoflavonoid Glycosides from the Rhizomes of Achyranthes Bidentata and Their Protective Effects on H2O2 Induced H9c2 Cardiomyocytes Injury. no. 110–117, Records of Natural Products, 2022.
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