Records of Natural Products

Records of Natural Products

A New Organic Acid Derivative from the Fruits of Rosa roxburghii

Yazarlar: Xin Yin, Yongqiang Zhou, Shuang Zhang, Ying Zhou

Cilt 16 , Sayı 3 , 2022 , Sayfalar 264-267

Konular:-

DOI:10.25135/rnp.276.21.07.2138

Anahtar Kelimeler:Rosaceae,Rosa roxburghii,Organic acid derivative

Özet: Phytochemical investigation of the fruits of Rosa roxburghii resulted in the isolation of four organic acid derivatives and three phenylpropanoids, including a new organic acid derivative, Roxbuacidester A (1) and six known compounds (2-7). The structures of all isolates were established by 1D and 2D NMR spectra referring to the literatures, together with HR-MS spectrometric analysis. In addition, compounds 1 and 2 were evaluated for their inhibitory activities on nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in a RAW 264.7 cell line. Compounds 1 and 2 showed moderate inhibition of NO production with IC50 values of 46.8 ± 2.3 and 62.5 ± 3.7 μM, respectively.

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@article{2022, title={ A New Organic Acid Derivative from the Fruits of Rosa roxburghii}, volume={16}, number={264–267}, publisher={Records of Natural Products}, author={Xin Yin, Yongqiang Zhou, Shuang Zhang, Ying Zhou}, year={2022} }
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Xin Yin, Yongqiang Zhou, Shuang Zhang, Ying Zhou. (2022). A New Organic Acid Derivative from the Fruits of Rosa roxburghii (Vol. 16). Vol. 16. Records of Natural Products.
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Xin Yin, Yongqiang Zhou, Shuang Zhang, Ying Zhou. A New Organic Acid Derivative from the Fruits of Rosa Roxburghii. no. 264–267, Records of Natural Products, 2022.
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