Harran Üniversitesi Tıp Fakültesi Dergisi

Yazarlar: İsmail BOYRAZ, Selma YAZICI, Bunyamin KOC, Ahmet YILDIZ, Umut GÜVEN

Konular:-

Anahtar Kelimeler:Arthritis,Juvenil,Macrophage Activation Syndrome

Özet: Still Disease is systemic inflammatory disease as a kind of Systemic Juvenil Rheumatoid Arthritis. Macrophage Activation Syndrome is a reason of mortality and morbidity at SOJIA. The 20 years old patient followed with the diagnosis of Still Disease for two years had been taking Methotrexate 15 mg/week, Plaquenil 200 mg/day. The patient turned to our clinic with complaints of common skin redness and arthralgia. In her test results, acute phase reactants were too high and when it was thought as illness activation, salazopyrine was added to the patient's treatment. The patient came to our clinic one week later with the complaints of throat pain lasting for 3-4 days and difficulty in swallowing. At the follow of the patient, deterioration of the patient's general condition and laboratory measures was found. We found during patient's physical examination common LAP and splenomegaly. Oral intake had stopped. Nausea, vomiting and temparature was going on. We wanted to consult to hematology department as to whether MAC syndrome diagnose was correct. Within a week of admitting the patient, bone marrow biopsy was made to correct MAC diagnosis and it proved to be true. The medical treatment was arranged as pulse steroid (1 gr/day), IVIG and Cyclosporin 100 mg 2*1. 

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