Harran Üniversitesi Tıp Fakültesi Dergisi

Yazarlar: Selim KUL, Muhammet Raşit SAYIN, İhsan DURSUN, Sinan ŞAHİN, Doğuş HEMŞİNLİ, Cihan AYDIN, Ahmet Hakan ATEŞ

Konular:Tıp

Anahtar Kelimeler:Diagonal earlobe crease,Platelet volume,Subclinical atherosclerosis

Özet: Background: Diagonal earlobe crease (DEL) is considered a sign of atherosclerosis. Platelets play an important role in the onset and subsequent complications of atherosclerotic lesions. Mean platelet volume (MPV) is an indicator of platelet activation. In this study, we aimed to evaluate MPV in DEL individuals. Material and Methods: Seventy-five patients with DEL (28F; mean age: 59±10 years) and 54 patients without DEL (23F; mean age: 56±11 years) were included in this study. Clinical and demographic characteristics, MPV, leukocyte counts, hemoglobin levels, platelet counts and plateletcrit levels were compared between the two groups. Results: Clinical and demographic characteristics were similar between the two groups. Hemoglobin levels (13.7±1.3 g/dL vs. 13.8±1.40 g/dL; p=0.782), leukocyte counts (7.01±1.57 x103mm-3 vs. 7.26±1.63 x103mm-3; p=0.429), platelet counts (240±57 x103mm-3 vs. 246±59 x103mm-3; p=0.617) and plateletcrit levels (0.207±0.048 % vs. 0.196±0.046%; p=0.258) were comparable between the two groups. MPV was significantly higher in the DEL group compared to non-DEL group (8.69±0.95 fL vs 7.96±0.75 fL; p<0.0001). Correlation analysis showed a significant but moderate correlation between DEL and MPV (p<0.0001; r = 0.356). Conclusion: MPV is elevated in patients with DEL. Considering the effects of platelets on atherosclerosis as well as their close relation to other risk factors, MPV may be an important predisposing factor for atherosclerosis in patients with DEL.

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