Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi

Yazarlar: Seren GÜNDOĞDU, Ayşe UZ

Konular:Farmakoloji ve Eczacılık

Anahtar Kelimeler:Enzyme,Lipases,Triacylglycerols,Lipase sources

Özet: Enzymes; They are protein catalyst biocatalysts that are specific to the substrate and are involved in many biological reactions inside and outside the cell. Lipases (triacylglycerol acyl hydrolases) are enzymes that catalyze the hydrolysis and synthesis of esters consisting of glycerol and long chain fatty acids. The use of non-toxic and environmentally friendly lipases is increasing day by day compared to other synthetic catalysts. In the food, chemical, fuel, paper and cellulose, pharmaceutical, cosmetic, perfume and cleaning industries, which adapt to the Industry 4.0 process we have reached today; By taking power from the developing biotechnological applications, new generation applications were used in which enzymes were used instead of traditional methods. At this point; The importance of lipases that are capable of sustainability in extreme conditions obtained by simple, sensitive, fast and specific enzyme purification methods used / developed is increasing day by day. In this review, the application areas of the lipase enzyme are mentioned and attention is drawn to the diversity of natural resources that can alleviate high enzyme costs in its production.

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