Records of Natural Products

Records of Natural Products

A New Angular Naphthopyrone from Crinoid Colobometra perspinosa

Yazarlar: Hsu-ming Chung, Ling-tsung Hsiao, Zong-you Li, Zhi-hong Wen

Cilt 15 , Sayı 3 , 2021 , Sayfalar 213-218

Konular:-

DOI:10.25135/rnp.207.20.07.1757

Anahtar Kelimeler:Angular naphthopyrone,Crinoid,Colobometra perspinosa,INOS

Özet: A chemical investigation was carried out on a crinoid Colobometra perspinosa collected from Hengchun Peninsula in the South China Sea, which led to the isolation of five angular naphthopyrones (1–5), including one new metabolite, 8-hydroxy-5,6,10-trimethoxy-2-pentyl-4H-naphtho[1,2-b]pyran-4-one (1). Their structures were assigned based on spectroscopic methods, including UV, HRESIMS, 1D- and 2D-NMR spectra. The anti-inflammatory activity of the isolated compounds was evaluated and compound 5 was found to inhibit the accumulation of the pro-inflammatory iNOS protein in LPS-stimulated RAW264.7 macrophages.

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@article{2021, title={A New Angular Naphthopyrone from Crinoid Colobometra perspinosa}, volume={15}, number={213–218}, publisher={Records of Natural Products}, author={Hsu-ming Chung, Ling-tsung Hsiao, Zong-you Li, Zhi-hong Wen}, year={2021} }
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Hsu-ming Chung, Ling-tsung Hsiao, Zong-you Li, Zhi-hong Wen. (2021). A New Angular Naphthopyrone from Crinoid Colobometra perspinosa (Vol. 15). Vol. 15. Records of Natural Products.
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Hsu-ming Chung, Ling-tsung Hsiao, Zong-you Li, Zhi-hong Wen. A New Angular Naphthopyrone from Crinoid Colobometra Perspinosa. no. 213–218, Records of Natural Products, 2021.
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