Records of Natural Products

Records of Natural Products

Three New Polyketides from the Insect-Associated Fungus Letendraea sp. 5XNZ4-2

Yazarlar: Yan Xu, Nanyan Fu, Wanjing Ding, Pinmei Wang, Jinzhong Xu

Cilt 15 , Sayı 3 , 2021 , Sayfalar 187-193

Konular:-

DOI:10.25135/rnp.206.20.08.1786

Anahtar Kelimeler:Polyketides,Insect-associated fungus,Letendraea sp.

Özet: Chemical investigation of the EtOAc extract of an insect-associated fungus Letendraea sp. 5XNZ4-2 cultured in Potato Dextrose Broth (1/2 PDB) medium lead to the isolation of three new polyketides, named letendronol D (1), phomopsiketones H-I (2-3). The structures of new compounds were elucidated by the analysis of HRESIMS and NMR spectroscopic data, and the absolute configurations were determined by modified Mosher’s method, ECD calculation and single-crystal X-ray diffraction. Cytotoxicity and antibacterial activities of 1 were assayed and regrettably 1 didn’t display any cytotoxicity and antibacterial activity. 3 was the first phomopsiketone derivative obtaining the lactone.

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@article{2021, title={Three New Polyketides from the Insect-Associated Fungus Letendraea sp. 5XNZ4-2}, volume={15}, number={187–193}, publisher={Records of Natural Products}, author={Yan Xu, Nanyan Fu, Wanjing Ding, Pinmei Wang, Jinzhong Xu}, year={2021} }
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Yan Xu, Nanyan Fu, Wanjing Ding, Pinmei Wang, Jinzhong Xu. (2021). Three New Polyketides from the Insect-Associated Fungus Letendraea sp. 5XNZ4-2 (Vol. 15). Vol. 15. Records of Natural Products.
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Yan Xu, Nanyan Fu, Wanjing Ding, Pinmei Wang, Jinzhong Xu. Three New Polyketides from the Insect-Associated Fungus Letendraea Sp. 5XNZ4-2. no. 187–193, Records of Natural Products, 2021.
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