The Turkish Journal of Vascular Surgery

Yazarlar: Mehmet Tercan, Mustafa Abanoz

Konular:-

Anahtar Kelimeler:Carotid artery disease,Coronary artery disease,Inflammation,Triglyceride

Özet: Objectives: In this study, we aimed to investigate the value of inflammatory biomarkers and atherogenicity index in predicting concomitant carotid artery stenosis (CAS) in patients undergoing coronary artery bypass grafting (CABG). Patients and methods: A total of 257 patients (163 males, 94 females; mean age 59.2±8 years; range, 33 to 75 years) admitted to our clinic and scheduled for isolated CABG between January 2016 and January 2019 were retrospectively analyzed. The patients were divided into two groups according to preoperative evaluation as those without significant CAS (Group 1, n=218) and those with CAS (≥50%) (Group 2, n=39). Results: The mean age was 55.9±7.9 in Group 1 and 65.7±9.4 in Group 2 (p<0.001). The mean platelet volume, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio were significantly higher in Group 2 (p=0.021, p=0.016, p=0.038, and p<0.001, respectively). In the multivariate analysis, age (odds ratio [OR]: 1.645, 95% confidence interval [CI]: 1.174-3.432, p=0.005), three-vessel/left main coronary artery disease (OR: 0.779, CI 95%: 0.576-0.912, p=0.021), and TG/HDL-C ratio (OR: 1.334, CI 95%: 1.190-2.785, p=0.015) were found to be independent predictors of concomitant significant CAS. Conclusion: Based on our study results, TG/HDL-C ratio, which can be measured from routine blood parameters, may be a useful predictor in predicting concomitant significant CAS in patients undergoing CABG.

---