Uluslararası Fen Araştırmalarında Yenilikçi Yaklaşımlar Dergisi

Yazarlar: Mert Metin , Özge Karakaş Metin

Konular:-

DOI:10.29329/ijiasr.2019.197.2

Anahtar Kelimeler:Saccharomyces cerevisiae,Arsenic,Signaling pathways,Cytotoxicity,Protein aggregation

Özet: Arsenic is a metalloid member of heavy metals associated with many health problems from various cancers to skin diseases. Due to mankind activities and natural sources, arsenic contamination seen globally. More than 150 million people globally face with arsenic via arsenic polluted ground water. It is well known that speciation of arsenic is important for its actions inside of the exposed organism. Saccharomyces cerevisiae, is one of six model organisms, provides an general answer for the question “What eukaryotes do?”. So assessing some questions on budding yeast gives a general idea about potential results in other eukaryotes including human. One of the issues investigated on this yeast is that impacts and metabolism of arsenic. Arsenic is well studied on Saccharomyces cerevisiae and consequently much data became available. In this review, cellular impacts of arsenic and response of the yeast towards arsenic exposure is covered.

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