Türk Bilimsel Derlemeler Dergisi

Yazarlar: Ayla ÖBER

Konular:-

Anahtar Kelimeler:Alzheimer disease,Tau tangles,Amyloid peptide,Amyloid plaques.

Özet: Alzheimer that indicate with mental defects is usually late on pretreatment application for perceiving ageriatric problem. Many factors cause to defects that damaged neurons transmissions on brain. For examples;virus, chemical messengers, proteins, genes, carbohydrates and calcium metabolism, environmental factors etc.This case in terms of molecular aspect is involved with proteins. These protein aggregations that developed intoneurons and among them, are attracted attention. This aggregation occurring into cells is resulted in constitutingneurofi brillary balls of tau protein and damaging structure and function of cell through bounding to tubulinprotein on microtubules structure. Whereas, constructions called amyloid plaques (β-amyloid peptide) amongneurons show an arrangement that point out also dementia intensity.

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