Türk Bilimsel Derlemeler Dergisi

Yazarlar: Dicle DÖNMEZ, Özhan ŞİMŞEK, Yıldız AKA KAÇAR

Konular:-

Anahtar Kelimeler:DNA sequencing,Genomics,Next-generation sequencing,Plant

Özet: High-throughput next generation DNA sequencing analysis has high potential in basic biological studies and genetic researches,therefore it emerges as one of the most important technologies used today. These technologies divide into three groups based on thesequencing method, sequencing by ligation, sequencing by synthesis and single molecule sequencing. The next-generation sequencingtechnologies offer novel and rapid ways for genome-wide characterization and profiling of mRNAs, small RNAs, transcription factorregions, structure of chromatin and DNA methylation patterns, microbiology and metagenomics. In this review the next generation DNAsequencing methods with their advantages and disadvantages, usage of these methods in the plant species were discussed.

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