Uluslararası Tarım Araştırmalarında Yenilikçi Yaklaşımlar Dergisi
Yazarlar: Review articles
Konular:-
DOI:10.29329/ijiaar.2019.217.17
Anahtar Kelimeler:BNRAMP1 gene,Genes structure,SNP,Diseases resistance
Özet: Bovine Natural Resistance Associated Macrophage Protein 1 (bNRAMP1) gene is one of the candidate gene that widely used to control the infectious disease in dairy and beef cattle. In mouse, the bNRAMP1 gene is important to confer resistance or suspectibility to Mycobacterium bovis, Salmonella typhimurium and Leishmania donovani. This article was carried out to explain the profile of bNRAMP gene such as genes structure, number of Single Nucleotide Polymorphisms (SNPs) and its relationship to pathogenic bacterial diseases evidence such as bovine Tuberculosis, mastitis and Brucellosis. The mutations (SNPs) in bNRAMP1 gene were occured in intron, exon and 3"UTR regions. Previous studies reported that some SNPs in bNRAMP1 gene affected to many pathogenic bacterial disease incidences in cattle. Hence, the bNRAMP1 gene can be used as the genetic marker for pathogenic bacterial resistance trait