Records of Natural Products

Yazarlar: Rong Yao , Shen Yao Ailian Hua

Konular:-

Anahtar Kelimeler:Aspergillus versicolor ,Aspeverether A ,Structure elucidation ,Marine

Özet: Chemical investigation of the EtOAc extract of a marine-derived fungus Aspergillus versicolor SZW-5 led to the isolation of one new compound, named aspeverether A (1), and seven known compounds. The structures were determined by extensive analyses of spectroscopic data (1D and 2D NMR, and HRESIMS). Compounds 1 and 3 possessed an unusual 1,3-dimethoxy-2-vinylbenzene moiety, which is rarely found in nature. Compound 6 showed strong inhibitory effect toward a-glucosidase with an IC50 value of 71 mM, being more active than the positive acarbose (210 mM).

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