Aydın Dental Journal

Yazarlar: Nil Ceren Mungan

Konular:Sağlık Bilimleri ve Hizmetleri

Anahtar Kelimeler:Laron syndrome,Growth hormone insensitivity

Özet: Aim: The purpose of this case report is to define oral-dental findings of Laron Syndrome. Laron syndrome, is a very rare familiar disorder with autosomal recessive transition. Case Report: A 11-year-old patient applied to Marmara University Faculty of Dentistry for dental treatment. She had growth inadequacy, small face and high pitched voice which are among the symptoms of the syndrome. Materials and Methods: In the intraoral examination, decays and crowded teeth on the upper jaw were observed due to small sized maxilla. The patient also had gingival inflammation due to the poor oral hygiene. The restorations were made and the patient was informed about the oral hygiene behaviors. Clinical Findings: Patients with Laron Syndrome have severe postnatal growth failure and a low level insulin like growth factor- 1(IGF-1). Children have very high-pitched voice, saddle nose, delayed puberty and delayed onset of teething. 

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