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Records of Natural Products
Yazarlar: Azza R. Abdel-Monem, Essam Abdel-Sattar, Fathalla M. Harraz, Frank Petereit
Konular:-
Anahtar Kelimeler:Euphorbia schimperi ,Triterpenoids ,Cycloartane,B -sitosterol- b -D-O-glucoside,Scopoletin,Luteolin,Kampferol,Cytotoxic activity.
Özet: Three triterpenoids; cycloart-25-en-3β,24-diol, cycloart-23-en-3β,25-diol, and a -amyrin, in addition to b -sitosterol- b -D-O-glucoside, scopoletin, luteolin and kampferol were isolated for the first time from the chloroform fraction of the alcoholic extract of Euphorbia schimperi C. Presl (F. Euphorbiaceae). The isolated compounds were identified using different spectroscopic methods (EIMS, 1HNMR, 13CNMR, HMQC, HMBC and COSY). The cytotoxic activity of the chloroform fraction was also studied using brain and breast carcinoma cell lines.