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Records of Natural Products
Yazarlar: Maria C. Palazzo, Brittany R. Agius, Brenda S. Wright, William A. Haber, Debra M. Moriarity William N. Setzer
Konular:-
Anahtar Kelimeler:Licaria excelsa ,Licaria triandra ,Persea schiedeana,Rhodostemonodaphne kunthiana,Essential oil composition,Lauraceae
Özet: The leaf essential oils of four members of the Lauraceae Licaria excelsa, Licaria triandra ,Persea schiedeana, and Rhodostemonodaphne kunthiana, from Monteverde , Costa Rica , were obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). The leaf oil of L. excelsa was dominated by the monoterpenes a -pinene (42.9%), b -pinene (22.0%) and myrcene (17.2%), while L. triandra was also rich in pinenes (40.9% and 28.5%, respectively). Persea schiedeana had considerable amounts of the sesquiterpenes d -cadinene (18.5%), a -copaene (15.1%), and (E)-caryophyllene (13.3%). Rhodostemonodaphne kunthiana leaf oil had germacrene D (64.4%) and bicyclogermacrene (17.6%) as the major components. The leaf essential oils were screened for in-vitro cytotoxic activity against MDA-MB-231 and Hs 578T human tumor cells. R. kunthiana leaf oil showed notable activity against MDA-MB-231.