Records of Natural Products

Yazarlar: Hidayat Hussain, Karsten Krohn, Siegfried eger, Kathrin Meier Barbara Schulz

Konular:-

Anahtar Kelimeler:Endophytic fungus,Meliotus dentatus ,Polyketides,Steroids,Biological activity.

Özet:  Chemical and biological investigations of the endophytic fungus of an unidentified Ascomycete, isolated from Meliotus dentatus led to the isolation of six known polyketide metabolites (1–6) and two steroids (7 and 8). Compounds 1–3, and 5 were tested for antibacterial, antialgal and antifungal activities. Compounds 2 , 3, and 5 showed good activity against the alga Chlorella fusca, while compounds 2 and 3 were active against the Gram negative bacterium Escherichia coli and compounds 3 and 5 also against the Gram positive Bacillus megaterium. Similarly, c ompounds 3 and 5 also showed antifungal activity against Microbotryum violaceum

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