Records of Natural Products

Records of Natural Products

Isolation and Biological Evaluation of Two Bioactive Metabolites from Aspergillus gorakhpurensis

Yazarlar: Siddhardha Busi, Prabhakar Peddikotla, Suryanarayana M. Upadyayula, Venkateswarlu Yenamra

Cilt 3 , Sayı 3 , 2009 , Sayfalar 161 - 164

Konular:-

Anahtar Kelimeler:Aspergillus gorakhpurensis,4-( N -methyl-N- phenyl amino) butan-2-one,Itaconic acid,Antibacterial,Spodoptera litura .

Özet: Fungi are known to produce a vast array of secondary metabolites that are gaining importance for their biotechnological applications. Screening ofAspergillus gorakhpurensis for the production of bioactive secondary metabolites results in the production of 4-(N-methyl-N-phenyl amino) butan-2-one and itaconic acid. The structure of the known compounds was established by 1H-, 13C-NMR and Mass spectral data. Biological evaluation of the two compounds against test microorganisms showed strong inhibitory activity of 4-(N-methyl-N-phenyl amino) butan-2-one towards bacteria and fungi. Only 4-( N -methyl-N- phenyl amino)-butan-2-one showed a marked significant activity (LD 50 = 330.69 m g/mL ) in Spodoptera litura larvicidal bioassay.

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@article{2009, title={Isolation and Biological Evaluation of Two Bioactive Metabolites from Aspergillus gorakhpurensis}, volume={3}, number={161–164}, publisher={Records of Natural Products}, author={Siddhardha Busi, Prabhakar Peddikotla, Suryanarayana M. Upadyayula, Venkateswarlu Yenamra}, year={2009} }
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Siddhardha Busi, Prabhakar Peddikotla, Suryanarayana M. Upadyayula, Venkateswarlu Yenamra. (2009). Isolation and Biological Evaluation of Two Bioactive Metabolites from Aspergillus gorakhpurensis (Vol. 3). Vol. 3. Records of Natural Products.
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Siddhardha Busi, Prabhakar Peddikotla, Suryanarayana M. Upadyayula, Venkateswarlu Yenamra. Isolation and Biological Evaluation of Two Bioactive Metabolites from Aspergillus Gorakhpurensis. no. 161–164, Records of Natural Products, 2009.
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