Records of Natural Products

Records of Natural Products

Antimalarial, Anticancer, Antimicrobial Activities and Chemical Constituents of Essential Oil from the Aerial Parts of Cyperus kyllingia Endl.

Yazarlar: Sorachai Khamsan, Boonsom Liawruangrath , Saisunee Liawruangrath, Aphiwat Teerawutkulrag , Stephen G. Pyne Mary J. Garson

Cilt 5 , Sayı 4 , 2011 , Sayfalar 324 - 327

Konular:-

Anahtar Kelimeler:Cyperus kyllingia Endl.,Essential oil,Antimalarial activity,Anticancer activity,Antimicrobial activity

Özet: The chemical constituents of the essential oil from Cyperus kyllingia Endl. were analyzed by a GC, GC-MS. Twenty-three compounds were identified, accounting for 93.75% of the total oil that consisted mainly of oxygenated sesquiterpenes (53.52%), particularly sesquiterpene hydrocarbons (38.97%), and carboxylic acid (1.26%). The most representative compounds were a -cadinol (19.32 %), caryophyllene oxide (12.17%), a -muurolol (11.58 %), a -humulene (9.85%), and a -atlantone (6.07%). The oil showed significant activities against Plasmodium falcipalum (K1, multi drug resistant strain) and NCI-H187 (Small Cell Lung Cancer) with the IC 50 values of 7.52 and 7.72 µg/mL, respectively. The oilexhibited highly active against Staphylococcus aureus ATCC25923 and moderately active against Escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27553, Aspergillus flavus and Candida albicans.

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@article{2011, title={Antimalarial, Anticancer, Antimicrobial Activities and Chemical Constituents of Essential Oil from the Aerial Parts of Cyperus kyllingia Endl.}, volume={5}, number={324–327}, publisher={Records of Natural Products}, author={Sorachai Khamsan, Boonsom Liawruangrath , Saisunee Liawruangrath, Aphiwat Teerawutkulrag , Stephen G. Pyne  Mary J. Garson}, year={2011} }
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Sorachai Khamsan, Boonsom Liawruangrath , Saisunee Liawruangrath, Aphiwat Teerawutkulrag , Stephen G. Pyne  Mary J. Garson. (2011). Antimalarial, Anticancer, Antimicrobial Activities and Chemical Constituents of Essential Oil from the Aerial Parts of Cyperus kyllingia Endl. (Vol. 5). Vol. 5. Records of Natural Products.
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Sorachai Khamsan, Boonsom Liawruangrath , Saisunee Liawruangrath, Aphiwat Teerawutkulrag , Stephen G. Pyne  Mary J. Garson. Antimalarial, Anticancer, Antimicrobial Activities and Chemical Constituents of Essential Oil from the Aerial Parts of Cyperus Kyllingia Endl. no. 324–327, Records of Natural Products, 2011.
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