Records of Natural Products

Records of Natural Products

Gas Chromatographic Determination of Quinolizidine Alkaloids in Genista sandrasica and Their Antimicrobial Activity

Yazarlar: Nurgün Küçükboyacı, Semiha Özkan Fatma Tosun

Cilt 6 , Sayı 1 , 2012 , Sayfalar 71 - 74

Konular:-

Anahtar Kelimeler:Genista sandrasica ,Fabaceae,Alkaloids,GC-MS,Antimicrobial activity.

Özet: Alkaloid profile of the aerial parts of Genista sandrasica Hartvig & Strid. (Fabaceae) growing in Turkey was studied by capillary gas chromatography-mass spectrometry (GC-MS). Ten quinolizidine alkaloids were identified in the alkaloid extract of G. sandrasica . The main alkaloids were: sparteine (13.68%), N-acetylcytisine (6.48%), 13-methoxylupanine (13.12%), anagyrine (40.49%) and baptifoline (10.76%). In addition, antibacterial and antifungal activities of the alkaloid extract of G. sandrasica were tested against standard strains of the bacteria (Escherichia coli , Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus) as well as the fungi (Candida albicans and Candida krusei). The alkaloid extract of G. sandrasica showed significant activity against B. subtilis and S. aureus with minimum inhibitory concentrations (MIC) of 31.25 and 62.5 µg/mL.

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@article{2012, title={Gas Chromatographic Determination of Quinolizidine Alkaloids in Genista sandrasica and Their Antimicrobial Activity}, volume={6}, number={71–74}, publisher={Records of Natural Products}, author={Nurgün Küçükboyacı, Semiha Özkan  Fatma Tosun}, year={2012} }
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Nurgün Küçükboyacı, Semiha Özkan  Fatma Tosun. (2012). Gas Chromatographic Determination of Quinolizidine Alkaloids in Genista sandrasica and Their Antimicrobial Activity (Vol. 6). Vol. 6. Records of Natural Products.
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Nurgün Küçükboyacı, Semiha Özkan  Fatma Tosun. Gas Chromatographic Determination of Quinolizidine Alkaloids in Genista Sandrasica and Their Antimicrobial Activity. no. 71–74, Records of Natural Products, 2012.
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