Records of Natural Products
Yazarlar: Niuniu Shi, Chunhua Lu, Coy Choke Ho, Yuemao Shen
Konular:-
Anahtar Kelimeler:Kitasatospora sp.,Kitasatodine,Kitasatopenoid,Spectroscopic,Cytotoxicity
Özet: A new pyridine-containing natural product, kitasatodine (1), and a new sesquiterpene, kitasatopenoid (2), together with a known cycloheximide (3) were isolated from the ethyl acetate extract of the strain H6549 (Kitasatospora sp.), which was isolated from dipterocarp forest of Kepong Kuala Lumpur in Malaysia. Their structures were established by spectroscopic methods including 1D and 2D-NMR experiments and HR-Q-TOF-MS. In addition, compounds 1and 2 showed moderate cytotoxicity against HeLa and HepG-2 cell lines.