Records of Natural Products

Records of Natural Products

Sapwood of Carob Tree (Ceratonia siliqua L.) as a Potential Source of Bioactive Compounds

Yazarlar: Luísa Custódio, Ana Luísa Escapa, João Patarra, Rosa Aligué, Ferno Alberício, Nuno Rosa Neng, José Manuel Florêncio Nogueira Anabela Romano

Cilt 7 , Sayı 3 , 2013 , Sayfalar 225 - 229

Konular:-

Anahtar Kelimeler:Antioxidant activity,Cytotoxic,Gentisic acid,Phenolic compounds,ROS.

Özet: Methanol (ME) and hot water extracts (WE) of carob tree sapwood (Ceratonia siliqua L.) exhibited high antioxidant activity and were rich in phenolic compounds, with the main compounds identified by HPLC/DAD as gentisic acid and (-)-epicatechin. The ME displayed a high in vitro antitumor activity against human tumoural cell lines and reduced intracellular ROS production by HeLa cells after treatment with H 2O 2. (-)-Epicatechin was shown to contribute to the cytotoxic activity of the ME. This is the first report on the biological activity of carob tree sapwood.

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@article{2013, title={Sapwood of Carob Tree (Ceratonia siliqua L.) as a Potential Source of Bioactive Compounds}, volume={7}, number={225–229}, publisher={Records of Natural Products}, author={Luísa Custódio, Ana Luísa Escapa, João Patarra, Rosa Aligué, Ferno Alberício, Nuno Rosa Neng, José Manuel Florêncio Nogueira  Anabela Romano}, year={2013} }
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Luísa Custódio, Ana Luísa Escapa, João Patarra, Rosa Aligué, Ferno Alberício, Nuno Rosa Neng, José Manuel Florêncio Nogueira  Anabela Romano. (2013). Sapwood of Carob Tree (Ceratonia siliqua L.) as a Potential Source of Bioactive Compounds (Vol. 7). Vol. 7. Records of Natural Products.
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Luísa Custódio, Ana Luísa Escapa, João Patarra, Rosa Aligué, Ferno Alberício, Nuno Rosa Neng, José Manuel Florêncio Nogueira  Anabela Romano. Sapwood of Carob Tree (Ceratonia Siliqua L.) as a Potential Source of Bioactive Compounds. no. 225–229, Records of Natural Products, 2013.
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