Records of Natural Products

Yazarlar: Gulmira Özek, Yerlan Suleimen, Nurhayat Tabanca, Roman Doudkin, Petr G. Gorovoy, Fatih Göger, David E. Wedge, Abbas Ali, Ikhlas A. Khan Kemal Hüsnü C. Başer

Konular:-

Anahtar Kelimeler:Artemisia ,Essential oil,Antifungal,Botanical insecticidal,Mosquito control,Antioxidant activity.

Özet: Artemisia argyi, A. feddei, A. gmelinii, A. manshurica, and A. olgensis (Asteraceae) were collected in Far East Russia. Oils were hydrodistilled and simultaneously analyzed by GC-FID and GC/MS. Main constituents were found as follows in Artemisia oils: selin-11-en-4 a -ol (18.0%), 1,8-cineole (14.2.0%), artemisia alcohol (12.9%), borneol (9.7%) in A. argyi; camphor (31.2%), 1,8-cineole (17.6%), a -thujone (5.7%) in A. feddei; longiverbenone (12.0%), isopinocamphone (8.9%), 1,8-cineole (6.7%), camphor (5.8%), trans-p-menth-2-en-1-ol (5.3%) in A. gmelinii; germacrene D (11.2%), rosifoliol (10.1%), caryophyllene oxide (6.8%), eudesma-4(15),7-dien-1 b -ol (5.6%) in A. manshurica; eudesma-4(15),7-dien-1 b -ol (6.9%), caryophyllene oxide (5.6%), guaia-6,10(14)-dien-4 b -ol (5.1%) and hexadecanoic acid (5.0%) in A. olgensis. Oils were subsequently submitted for antifungal and antimosquito evaluations. Artemisia species oils showed biting deterrent effects in Aedes aegypti and Artemisia gmelinii oil with the most active biting deterrence index values of 0.82 ± 0.1 at 10 m g/mL. Larval bioassay of A. gmelinii and A. olgensis oils showed higher larvicidal activity against Ae. aegypti larvae with LD50 values of 83.8 (72.6 – 95.7) ppm and 91.0 (73.8 – 114.5) ppm, respectively. Antifungal activity was evaluated against the strawberry anthracnose-causing fungal plant pathogens Colletotrichum acutatum, C. fragariae and C. gloeosporioides using direct overlay bioautography assay and all showed non-selective weak antifungal activity. Antioxidant evaluations of the oils were performed by using b -carotene bleaching, Trolox equivalent and DPPH tests. The tested Artemisia oils demonstrated moderate antioxidant activity.

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