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Records of Natural Products
Yazarlar: Qin Zhu, Ligen Lin, Chunping Tang, Changqiang Ke Yang Ye
Konular:-
Anahtar Kelimeler:Melia toosendan ,Triterpenoids ,Meliaceae ,Antibacterial
Özet: A new lanostan-type triterpenoid with hydroperoxy group, toosendanin A (1), together with two known triterpenoids, meliastatin 3 (2) and ursolic acid (3), w ere isolated and identified from the stems of Melia toosendan. The structures of these compounds were elucidated by 1D- and 2D-NMR spectra and other spectroscopic studies. These compounds were assayed for the antibacterial activities against some hospital pathogenic bacteria. Toosendanin A (1) exhibited strong antibacterial activity against K. pneumoniae .