Records of Natural Products

Records of Natural Products

A New Amide from the Stem Bark of Illiciumdifengpi and Its Anti-inflammatory Activity

Yazarlar: Chuntong Li, Zhijun Wu Wansheng Chen

Cilt 9 , Sayı 2 , 2015 , Sayfalar 257 - 261

Konular:-

Anahtar Kelimeler:Amide,Illicium difengpi,Anti-inflammatory

Özet: A new amide, named ( 2E, 4E)-5-phenyl-N-(2-phenylethyl)-2,4-pentadienamide (1) , together with one known amide, N -2-phenylet hylcinnamide (2) and two known ceramides, 2-​hydroxy-​N-​[(1S,​2R,​3E)​-​2-​hydroxy-​1-​(hydroxymethyl)​-​3-​heptadecenyl]​-pentadecanamide (3), 1-O-(β-D-glucopyranosyl)-(2S,3R,4E,8E)-2-[(2R)-2-hydroxypentadecanoylamino]-4,8-octadecadiene-1,3-diol (4) were isolated from the stem bark of Illicium difengpi. The structures of the isolated compounds were elucidated by analyses of their 1H and 13C NMR, COSY, H S QC, HMBC spectr a and HR-ESI/MS mass spectrometric data. Anti-inflammatory assays with compounds 1‒4 were carried out, compounds 1 and 2 showed significant inhibitory effect on TNF- α release in LPS stimulated RAW 264.7 macrophages.

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@article{2015, title={A New Amide from the Stem Bark of Illiciumdifengpi and Its Anti-inflammatory Activity}, volume={9}, number={257–261}, publisher={Records of Natural Products}, author={Chuntong Li, Zhijun Wu*  Wansheng Chen}, year={2015} }
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Chuntong Li, Zhijun Wu*  Wansheng Chen. (2015). A New Amide from the Stem Bark of Illiciumdifengpi and Its Anti-inflammatory Activity (Vol. 9). Vol. 9. Records of Natural Products.
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Chuntong Li, Zhijun Wu*  Wansheng Chen. A New Amide from the Stem Bark of Illiciumdifengpi and Its Anti-Inflammatory Activity. no. 257–261, Records of Natural Products, 2015.
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