Records of Natural Products
Isolation, Structure Determination, In Vivo/Vitro Assay and Docking Study of a Xanthone with antitumor activity from Fungus Penicillium oxalicum
Yazarlar: Gang Chen, Zhe Jiang, Jiao Bai, Haifeng Wang, Shuling Zhang Yuehu Pei
Cilt 9 , Sayı 2 , 2015 , Sayfalar 184 - 189
Konular:-
Anahtar Kelimeler:Xanthone,Antitumor,Docking
Özet: Investigation of EtOAc extract from the fermentation broth of the fungus Penicillium oxalicum led to the isolation of a xanthone, secalonic acid D, which showed good antitumor activity both in vivo and in vitro. The docking study revealed that secalonic acid D could block the active pocket of topoisomerase І with seven hydrogen bonds between secalonic acid D and ARG488, LYS532, ASP533.
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Atıf Yapan Eserler
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BibTex
KOPYALA
@article{2015, title={Isolation, Structure Determination, In Vivo/Vitro Assay and Docking Study of a Xanthone with antitumor activity from Fungus Penicillium oxalicum}, volume={9}, number={184–189}, publisher={Records of Natural Products}, author={Gang Chen, Zhe Jiang, Jiao Bai, Haifeng Wang, Shuling Zhang Yuehu Pei}, year={2015} }
APA
KOPYALA
Gang Chen, Zhe Jiang, Jiao Bai, Haifeng Wang, Shuling Zhang Yuehu Pei. (2015). Isolation, Structure Determination, In Vivo/Vitro Assay and Docking Study of a Xanthone with antitumor activity from Fungus Penicillium oxalicum (Vol. 9). Vol. 9. Records of Natural Products.
MLA
KOPYALA
Gang Chen, Zhe Jiang, Jiao Bai, Haifeng Wang, Shuling Zhang Yuehu Pei. Isolation, Structure Determination, In Vivo/Vitro Assay and Docking Study of a Xanthone with Antitumor Activity from Fungus Penicillium Oxalicum. no. 184–189, Records of Natural Products, 2015.