Records of Natural Products
Yazarlar: Luis Enrique Cuca-Suarez, Franco Della-Monache Ericsson Coy-Barrera
Konular:-
Anahtar Kelimeler:Amyris pinnata,Lignans,Coumarins,Alkaloid,Flavonoid,Cytotoxicity
Özet: From leaves and bark of Amyris pinnata Kunth twelve compounds were isolated, corresponding to six lignans 1-6, three coumarins 7-9, a sesquiterpene 10, an oxazole alkaloid 11, and a prenylated flavonoid 12,. Metabolites were identified by spectroscopic techniques ( 1H and 13C NMR, EIMS) and by comparison with published data in the literature. C ytotoxicity against leukemia, solid tumors, and normal cells was evaluated for all isolated compounds. Lignans were found to be the most cytotoxic compounds occurring in A. pinnata.