Records of Natural Products

Records of Natural Products

Chemical Characterization and Acetylcholinesterase Inhibition Potential of Volatile Components of Aerial Parts of Pluchea lanceolata (DC.) Oliv. & Hiern

Yazarlar: Pooja Srivastava, Jyotshna, Debabrata Cha Karuna Shanker

Cilt 9 , Sayı 4 , 2015 , Sayfalar 586 - 591

Konular:-

Anahtar Kelimeler:Pluchea lanceolata,Volatile organic contents (VOCs),Acetylcholinesterase inhibition,GC-MS,NMR

Özet: Pluchea lanceolata (DC.) Oliv. & Hiern (Rasana) is an important medicinal plant due to its usage in number of Ayurvedic formulations. First time, chemical composition of essential oil from the aerial part of P. lanceolata was analyzed by gas chromatography-mass spectrometry (GC-MS) and NMR spectroscopy. Ex-vivo cholinesterase inhibitory activity of the essential oil was also evaluated using mouse brain homogenate. The major components were linalool (32.2%), β-caryophyllene (8.5%), α-terpineol (8.0%), spathulenol (7.4%), linalylacetate (5.6%), naphthalene, 1,6-dimethyl-4-(1-methylethyl)- (4.3%), α-copaene (3.6%), epi-cubebol (3.6%) and trans-α-bergamontene (3.1%). The experimental results showed that hydrodistilate of P. lanceolata significantly inhibited acetylcholinesterase activity (IC 50 value 2.54 ± 0.03 µg/mL).

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@article{2015, title={Chemical Characterization and Acetylcholinesterase Inhibition Potential of Volatile Components of Aerial Parts of Pluchea lanceolata (DC.) Oliv. & Hiern}, volume={9}, number={586–591}, publisher={Records of Natural Products}, author={Pooja Srivastava, Jyotshna1, Debabrata Cha2  Karuna Shanker}, year={2015} }
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Pooja Srivastava, Jyotshna1, Debabrata Cha2  Karuna Shanker. (2015). Chemical Characterization and Acetylcholinesterase Inhibition Potential of Volatile Components of Aerial Parts of Pluchea lanceolata (DC.) Oliv. & Hiern (Vol. 9). Vol. 9. Records of Natural Products.
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Pooja Srivastava, Jyotshna1, Debabrata Cha2  Karuna Shanker. Chemical Characterization and Acetylcholinesterase Inhibition Potential of Volatile Components of Aerial Parts of Pluchea Lanceolata (DC.) Oliv. & Hiern. no. 586–591, Records of Natural Products, 2015.
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