Records of Natural Products

Records of Natural Products

New γ -Lactone Carboxylic Acids from the Lichen Parmotrema praesorediosum (Nyl.) Hale, Parmeliaceae

Yazarlar: Bui Linh Chi Huynh, Thuc Huy Duong, Thi My Lien Do, Travis George Pinnock, Lawrence Michael Pratt, Shigeki Yamamoto, Hitoshi Watarai, Takao Tanahashi Kim Phi Phung Nguyen

Cilt 10 , Sayı 3 , 2016 , Sayfalar 332 - 340

Konular:-

Anahtar Kelimeler:Parmotrema praesorediosum,Parmeliaceae,Lichen,Aliphatic acids

Özet: From the lichen Parmotrema praesorediosum (Nyl.) Hale, Parmeliaceae, collected in Vietnam, five new (1, 2, 3, 5, 6) and one known (4) g -lactonic acids were isolated. The structures of the new compounds were established by 1D and 2D NMR spectroscopy, as well as high resolution-electrospray ionization (HR-ESI)-MS analysis. The absolute configuration of new compounds was determined by ultraviolet circular dichroism spectroscopy. Compounds were evaluated for their cytotoxic activity against HeLa (human epithelial carcinoma), NCI-H460 (human lung cancer) and MCF-7 (human breast cancer) cell lines at the concentration of 100 µg/mL. Among six compounds, 1 possessed medium activity against MCF-7 cell line with the inhibition of 52.5%. Meanwhile, the rest showed no cytotoxic activity against three surveyed cancer cell lines.

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@article{2016, title={New  γ -Lactone  Carboxylic Acids from the Lichen Parmotrema praesorediosum (Nyl.) Hale, Parmeliaceae}, volume={10}, number={332–340}, publisher={Records of Natural Products}, author={Bui Linh Chi Huynh, Thuc Huy Duong, Thi My Lien Do, Travis George Pinnock, Lawrence Michael Pratt, Shigeki Yamamoto, Hitoshi Watarai, Takao Tanahashi  Kim Phi Phung Nguyen}, year={2016} }
APA
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Bui Linh Chi Huynh, Thuc Huy Duong, Thi My Lien Do, Travis George Pinnock, Lawrence Michael Pratt, Shigeki Yamamoto, Hitoshi Watarai, Takao Tanahashi  Kim Phi Phung Nguyen. (2016). New  γ -Lactone  Carboxylic Acids from the Lichen Parmotrema praesorediosum (Nyl.) Hale, Parmeliaceae (Vol. 10). Vol. 10. Records of Natural Products.
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Bui Linh Chi Huynh, Thuc Huy Duong, Thi My Lien Do, Travis George Pinnock, Lawrence Michael Pratt, Shigeki Yamamoto, Hitoshi Watarai, Takao Tanahashi  Kim Phi Phung Nguyen. New  γ -Lactone  Carboxylic Acids from the Lichen Parmotrema Praesorediosum (Nyl.) Hale, Parmeliaceae. no. 332–340, Records of Natural Products, 2016.
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