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Records of Natural Products
Yazarlar: Theodora K. Kowa, Denis Zofou, Roukayatou Mbouangouere, Michel F. Tala, Hippolyte K. Wabo, Ning-Hua Tan, Vincent P.K. Titanji Pierre Tane
Konular:-
Anahtar Kelimeler:Anthocleista liebrechtsiana,Loganiaceae,Cerebroside,Structure elucidation,Antiplasmodial activity
Özet: One new cerebroside derivative, namely liebrechtsianoside A (1), along with five known compounds: tetracosanoic acid (2), swertiaperennin (3), decussatin (4), swertianin (5) and β-sitosterol glucoside (6) were isolated from the the stem bark of Anthocleista liebrechtsiana . Their structures were elucidated by interpretation of NMR and MS data, and by comparison of these data with those reported in literature. Compound 1 showed the highest antiplasmodial activity against Dd2 chloroquine-resistant strain of Plasmodium falciparum.