![Records of Natural Products](https://asosindex.com.tr/dergi-img/RoNp_kapak.jpg)
Records of Natural Products
Yazarlar: Desheng Liu, Yuling Huang, Chunmin Li, Liying Ma, Xiaohong Pan, Daneel Ferreira Weizhong Liu
Konular:-
Anahtar Kelimeler:Secondary metabolites,Aspergillus fumigatus,Cytotoxic activity,Coastal saline soil
Özet: A new sesquiterpenoid derivative, named aspergiketone (1), along with seven known compounds (2-8) were isolated from the coastal saline soil fungus Aspergillus fumigatus. Their structures were elucidated by spectroscopic analysis, and by comparison of experimental and reported data. The absolute configuration of compound 1 was defined by X-ray diffraction analysis. Compound 1 was cytotoxic towards HL-60 and A549 cell lines with IC 50 values of 12.4 and 22.1 μ M , respectively.