Records of Natural Products

Yazarlar: Hadjira Dakiche, Mustapha Khali Houcine Boutoumi

Konular:-

Anahtar Kelimeler:Argania spinosa (L.) Skeels,Oil,Chemical composition,Anti-inflammatory,Wound-healing.

Özet: The extracted oil of Argania spinosa (L.) was investigated in regard to its fatty acid composition and polyphenols by Gas Chromatography-Mass Spectrometry (GC–MS) and Ultra-high Performance Liquid Chromatography-Electro Spray Ionization-Quadruple Time Of Flight-Mass Spectrometry (UPLC-ESI-QTOF-MS), respectively. The reduction rate of topical inflammation of extracted oil was calculated using a mouse model. The skin toxicity of argan oil on intact and damaged skin was assessed using a rabbit model. The findings revealed a rich content of monounsaturated and polyunsaturated fatty acids and presence of phenolic acids. The oil exhibited a reduction of inflammation and facilitated a healing process without any irritation. The experimental study revealed that A. spinosa seed oil displays remarkable wound-healing and anti-inflammatory activities related to its chemical composition. Argan oil has positive potential for skin medicinal application.

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