Records of Natural Products

Records of Natural Products

New Secondary Metabolites from an Endophytic Fungus in Porodaedaleapini

Yazarlar: Shuen -Shin Yang, Ming-Jen Cheng, Hing-Yuen Chan, Sung-Yuan Hsieh, Ho-Cheng Wu, Gwo - Fang Yuan, Chu-Hung Lin, Hsun-Shuo Chang Ih -Sheng Chen

Cilt 11 , Sayı 3 , 2017 , Sayfalar 251 - 257

Konular:-

Anahtar Kelimeler:Porodaedalea pini,Fungus,Benzenoids,NO inhibitory activity,Androgen antagonism.

Özet: Eight benzenoids including three new phenols, piniphenols A–C (1–3), along with five known compounds, 4-vinylphenol (4) and 4-hydroxybenzaldehyde (5), 2-methoxy-2-(4'-hydroxyphenyl)ethanol (6), 2,3-dihydroxypropyl acetate (7), and phenol (8) were isolated from ethyl acetate layer of liquid fermentation with Porodaedalea pini (Hymenochaetaceae) BCRC 35384. All structures were established by spectral analysis and comparison with the literature data. Of these isolates, 1 showed moderate NO inhibitory activity with an IC 50 value of 60.0 μM . Compound 1 also showed the androgen receptor (AR) antagonism with the IC 50 value of 0.42 μM. To the best of our knowledge, this is the first report on benzenoid metabolites from the genus Porodaedalea .

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@article{2017, title={New Secondary Metabolites from an Endophytic Fungus in Porodaedaleapini}, volume={11}, number={251–257}, publisher={Records of Natural Products}, author={Shuen -Shin Yang, Ming-Jen Cheng, Hing-Yuen Chan, Sung-Yuan Hsieh, Ho-Cheng Wu, Gwo - Fang Yuan, Chu-Hung Lin, Hsun-Shuo Chang  Ih -Sheng Chen}, year={2017} }
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Shuen -Shin Yang, Ming-Jen Cheng, Hing-Yuen Chan, Sung-Yuan Hsieh, Ho-Cheng Wu, Gwo - Fang Yuan, Chu-Hung Lin, Hsun-Shuo Chang  Ih -Sheng Chen. (2017). New Secondary Metabolites from an Endophytic Fungus in Porodaedaleapini (Vol. 11). Vol. 11. Records of Natural Products.
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Shuen -Shin Yang, Ming-Jen Cheng, Hing-Yuen Chan, Sung-Yuan Hsieh, Ho-Cheng Wu, Gwo - Fang Yuan, Chu-Hung Lin, Hsun-Shuo Chang  Ih -Sheng Chen. New Secondary Metabolites from an Endophytic Fungus in Porodaedaleapini. no. 251–257, Records of Natural Products, 2017.
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