Records of Natural Products

Records of Natural Products

Antileishmanial Activity of a New ent-Kaurene Diterpene Glucoside Isolated from Leaves of Xylopia excellens R.E.Fr. (Annonaceae)

Yazarlar: Danielle C. Alencar, Felipe M. A. da Silva, Richardson A. de Almeida, Emmanoel V. Costa, Lívia M. Dutra, Andersson Barison, Helito Volpato, Celso V. Nakamura, Hector H. F. Koolen, Afonso Duarte L. de Souza Maria Lúcia B. Pinheiro

Cilt 12 , Sayı 2 , 2018 , Sayfalar 190 - 194

Konular:-

Anahtar Kelimeler:Annonaceae,Ent-kaurene diterpene,Leishmania amazonensis,Xylopia excellens.

Özet: This work describes a new ent-kaurene diterpene glucoside, 7β-O-β-D-glucopyranoside-ent-kaur-16-ene, from the leaves of Xylopia excellens R.E.Fr. (Annonaceae). The compound showed high in vitro antileishmanial activity (IC 50 of 15.23 ± 0.64 µg/mL) towards promastigote forms of Leishmania amazonensis, and low cytotoxicity against J774A1 cells (SI of 1.96).

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@article{2018, title={Antileishmanial Activity of a New ent-Kaurene Diterpene Glucoside Isolated from Leaves of Xylopia excellens R.E.Fr. (Annonaceae)}, volume={12}, number={190–194}, publisher={Records of Natural Products}, author={Danielle C. Alencar, Felipe M. A. da Silva, Richardson A. de Almeida, Emmanoel V. Costa, Lívia M. Dutra, Andersson Barison, Helito Volpato, Celso V. Nakamura, Hector H. F. Koolen, Afonso Duarte L. de Souza  Maria Lúcia B. Pinheiro}, year={2018} }
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Danielle C. Alencar, Felipe M. A. da Silva, Richardson A. de Almeida, Emmanoel V. Costa, Lívia M. Dutra, Andersson Barison, Helito Volpato, Celso V. Nakamura, Hector H. F. Koolen, Afonso Duarte L. de Souza  Maria Lúcia B. Pinheiro. (2018). Antileishmanial Activity of a New ent-Kaurene Diterpene Glucoside Isolated from Leaves of Xylopia excellens R.E.Fr. (Annonaceae) (Vol. 12). Vol. 12. Records of Natural Products.
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Danielle C. Alencar, Felipe M. A. da Silva, Richardson A. de Almeida, Emmanoel V. Costa, Lívia M. Dutra, Andersson Barison, Helito Volpato, Celso V. Nakamura, Hector H. F. Koolen, Afonso Duarte L. de Souza  Maria Lúcia B. Pinheiro. Antileishmanial Activity of a New Ent-Kaurene Diterpene Glucoside Isolated from Leaves of Xylopia Excellens R.E.Fr. (Annonaceae). no. 190–194, Records of Natural Products, 2018.
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