Records of Natural Products

Records of Natural Products

Wound Healing Effect of Flavonoid Glycosides from Afgekia mahidolae B.L.Burtt & Chermsir. Leaves

Yazarlar: Chalermlat Suktap, Hyeong Kyu Lee , Surattana Amnuaypol , Rutt Suttisri Suchada Sukrong

Cilt 12 , Sayı 4 , 2018 , Sayfalar 391 - 396

Konular:-

Anahtar Kelimeler:Afgekia mahidolae ,Fibroblasts,Flavonoid glycosides,Scratch-wound healing

Özet: Five known flavonoid glycosides namely, juglanin (1), astragalin (2), nicotiflorin (3), isoquercetin (4) and apigenin-7-O- b -glucuronide (5), and a phenolic glucoside, arbutin (6), were isolated for the first time from the leaves of Afgekia mahidolae (Fabaceae). Their structures were elucidated using one- and two-dimensional NMR spectroscopic methods and comparison with the literature. The ability of 1-4 to promote the migration of CCD-1064sk fibroblasts into a scratch-wound area was evaluated. The results indicated that juglanin (1) and nicotiflorin (3) significantly increased the migration of these cells and, hence, supporting the wound healing effect of flavonol glycosides.

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@article{2018, title={Wound Healing Effect of Flavonoid Glycosides from Afgekia mahidolae B.L.Burtt & Chermsir. Leaves}, volume={12}, number={391–396}, publisher={Records of Natural Products}, author={Chalermlat Suktap, Hyeong Kyu Lee , Surattana Amnuaypol , Rutt Suttisri  Suchada Sukrong}, year={2018} }
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Chalermlat Suktap, Hyeong Kyu Lee , Surattana Amnuaypol , Rutt Suttisri  Suchada Sukrong. (2018). Wound Healing Effect of Flavonoid Glycosides from Afgekia mahidolae B.L.Burtt & Chermsir. Leaves (Vol. 12). Vol. 12. Records of Natural Products.
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Chalermlat Suktap, Hyeong Kyu Lee , Surattana Amnuaypol , Rutt Suttisri  Suchada Sukrong. Wound Healing Effect of Flavonoid Glycosides from Afgekia Mahidolae B.L.Burtt & Chermsir. Leaves. no. 391–396, Records of Natural Products, 2018.
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