Records of Natural Products

Yazarlar: Shaymaa Al-Majmaie, Lutfun Nahar, George P. Sharples, Khazal Wadi Satyajit D. Sarker

Konular:-

Anahtar Kelimeler:Ruta chalepensis ,Rutaceae,Resazurin assay,Antimicrobial activity,Rutin ,6-hydroxy-rutin 3‵,7-dimethyl ether

Özet: Rutin (1), rutin 3'-methyl ether (2), and a new flavonol glycoside, 6-hydroxy-rutin 3',7-dimethyl ether (3), were isolated from the methanol extract of the fruits of Ruta chalepensis , collected from Diyala, Iraq. Their structures were elucidated by spectroscopic analyses, including 1D-, 2D-NMR and HR ESI MS. Antimicrobial activity of compounds 1-3 was tested against four Gram +ve and Gram –ve bacterial strains, and the only fungal strain, Candida albicans, using the 96-well based resazurin microtitre assay.

---