Records of Natural Products

Records of Natural Products

New Cytotoxic Metabolites from Pathogenic Fungus Cylindrocarpon destructans Associated with Meconopsis grandis

Yazarlar: Dilfaraz Khan, Shah Iram Niaz, Kamran Tahir, Hidayat Ullah Khan, Muhammad Haroon, Shahid Ullah Khan, Syed Badshah, Shafiullah Khan, Muafia Jabeen Liu Lan

Cilt 13 , Sayı 2 , 2019 , Sayfalar 129 - 135

Konular:-

Anahtar Kelimeler:Pathogenic fungus,Cylindrocarpon destructans,Meconopsis grandis,Cytotoxic activity

Özet: Phytochemical investigation on pathogenic fungus Cylindrocarpon destructans isolated form Meconopsisgrandis plant led to the isolation of two new isochromene derivatives namely, 6,8-dimethoxy-3-methyl-3,4-dihydrobenzoisochromene-4,9,10-triol (1) and 3,5,6-trihydroxy-4-methylbenzoisochromene-9,11-dione (2) along with four known compounds (3-6). The structures of these compounds were elucidated by 1D and 2D NMR and mass spectroscopic data analysis. The isolated compounds were evaluated for cytotoxic activity. The compounds 1-4 showed good inhibition against the growth of cell lines MCF-7 and PC-3. Compounds 5-6 showed minimum inhibitory effect of cancerous cell lines growth.

ATIFLAR
Atıf Yapan Eserler
Henüz Atıf Yapılmamıştır
KAYNAK GÖSTER
BibTex
KOPYALA
@article{2019, title={New Cytotoxic Metabolites from Pathogenic Fungus Cylindrocarpon destructans Associated with Meconopsis grandis}, volume={13}, number={129–135}, publisher={Records of Natural Products}, author={Dilfaraz Khan, Shah Iram Niaz, Kamran Tahir, Hidayat Ullah Khan, Muhammad Haroon, Shahid Ullah Khan, Syed Badshah, Shafiullah Khan, Muafia Jabeen  Liu Lan}, year={2019} }
APA
KOPYALA
Dilfaraz Khan, Shah Iram Niaz, Kamran Tahir, Hidayat Ullah Khan, Muhammad Haroon, Shahid Ullah Khan, Syed Badshah, Shafiullah Khan, Muafia Jabeen  Liu Lan. (2019). New Cytotoxic Metabolites from Pathogenic Fungus Cylindrocarpon destructans Associated with Meconopsis grandis (Vol. 13). Vol. 13. Records of Natural Products.
MLA
KOPYALA
Dilfaraz Khan, Shah Iram Niaz, Kamran Tahir, Hidayat Ullah Khan, Muhammad Haroon, Shahid Ullah Khan, Syed Badshah, Shafiullah Khan, Muafia Jabeen  Liu Lan. New Cytotoxic Metabolites from Pathogenic Fungus Cylindrocarpon Destructans Associated with Meconopsis Grandis. no. 129–135, Records of Natural Products, 2019.
Atıf Görüntüle
PDF Görüntüle
Kaynak Görüntüle
Paylaş
Dergi Bilgileri