Records of Natural Products

Records of Natural Products

Polyacetylenes from the Roots of Aralia dumetorum

Yazarlar: Meng-Yuan Jiang , Chun-Tao Yang , Xiao-Yun Pu , Guangmiao Fu , Wei Wang , Yu-Xiao Li , Lei Feng , Zhi-Rui Niu , Jian-Lin Tan Xiang-Zhong Huang

Cilt 13 , Sayı 5 , 2019 , Sayfalar 424 - 428

Konular:-

Anahtar Kelimeler:Araliaceae ,Aralia dumetorum ,Polyacetylenic compound ,Α-glucosidase inhibitor

Özet: A new polyacetylene, heptadeca-8,16-dien-4,6-diyn-3,l0-diol (1) along with four known polyacetylenes, 1,2-dihydrodendroarboreol B (2), heptadeca-1,8-dien-4,6-diyn-3,l0-diol (3), 3R, 8S-falcarindiol (4) and 3R,8R-dehydrofalcarindiol (5) were isolated from the ethanol extract of Aralia dumetorum. The structures of the isolates were elucidated on the basis of 1D and 2D NMR spectrums and by comparison of the spectroscopic data with those reported for structurally related compounds. The α-glucosidase inhibitory activity of compounds 1-5 was evaluated using α-glucosidase inhibitory assay, in which all compounds displayed good inhibitory activity with IC50 values ranging from 4.2 ~ 36.2 μM..

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@article{2019, title={Polyacetylenes from the Roots of Aralia dumetorum}, volume={13}, number={424–428}, publisher={Records of Natural Products}, author={Meng-Yuan Jiang , Chun-Tao Yang , Xiao-Yun Pu , Guangmiao Fu , Wei Wang , Yu-Xiao Li , Lei Feng , Zhi-Rui Niu , Jian-Lin Tan  Xiang-Zhong Huang}, year={2019} }
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Meng-Yuan Jiang , Chun-Tao Yang , Xiao-Yun Pu , Guangmiao Fu , Wei Wang , Yu-Xiao Li , Lei Feng , Zhi-Rui Niu , Jian-Lin Tan  Xiang-Zhong Huang. (2019). Polyacetylenes from the Roots of Aralia dumetorum (Vol. 13). Vol. 13. Records of Natural Products.
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Meng-Yuan Jiang , Chun-Tao Yang , Xiao-Yun Pu , Guangmiao Fu , Wei Wang , Yu-Xiao Li , Lei Feng , Zhi-Rui Niu , Jian-Lin Tan  Xiang-Zhong Huang. Polyacetylenes from the Roots of Aralia Dumetorum. no. 424–428, Records of Natural Products, 2019.
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