Records of Natural Products

Records of Natural Products

Cytotoxic Lathyrane Diterpenoids from the Roots of Euphorbia fischeriana

Yazarlar: Jue Li , Jianlin He , Chunai Yang , Xuelong Yan Zhao Yin

Cilt 14 , Sayı 4 , 2020 , Sayfalar 286 - 291

Konular:-

Anahtar Kelimeler:Euphorbia fischeriana ,Euphorbiaceae ,Lathyrane ,Diterpenoid

Özet: Two new lathyrane diterpenoids, euphofischers A and B (1 and 2), along with three known analogues (3-5), were isolated from the roots of Euphorbia fischeriana. Their structures were elucidated by spectroscopic analysis. Euphofischer A (1) represents rare example of a lathyrane diterpenoid featuring a 15-p-coumaroyl moiety. All compounds were screened for their cytotoxicity against three cancer cell lines (C4-2B, C42B/ENZR, and MDA-MB-231), and  compound 1 exhibited significant cytotoxicity against C4-2B cell line, with an IC50 value of 11.3 mM.

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@article{2020, title={Cytotoxic Lathyrane Diterpenoids from the Roots of Euphorbia fischeriana}, volume={14}, number={286–291}, publisher={Records of Natural Products}, author={Jue Li , Jianlin He , Chunai Yang , Xuelong Yan  Zhao Yin}, year={2020} }
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Jue Li , Jianlin He , Chunai Yang , Xuelong Yan  Zhao Yin. (2020). Cytotoxic Lathyrane Diterpenoids from the Roots of Euphorbia fischeriana (Vol. 14). Vol. 14. Records of Natural Products.
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Jue Li , Jianlin He , Chunai Yang , Xuelong Yan  Zhao Yin. Cytotoxic Lathyrane Diterpenoids from the Roots of Euphorbia Fischeriana. no. 286–291, Records of Natural Products, 2020.
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