Records of Natural Products
Yazarlar: Zhang Xiaopo , Zhang Caiyun , Chen Lizhen , Li Yiying , Na Wei , Zhang Lu , Dong Lin Zhang Yong
Konular:-
Anahtar Kelimeler:Scoparia dulcis L ,Scoparic acid E ,Labdane diterpenoid ,Palmitate-induced viability
Özet: A new labdane diterpenoid, named Scoparic acid E (1), was obtained from the medicinal plant of Scoparia dulcis L. The structure of Scoparic acid E (1) was elucidated and characterized through detailed physical analyses of its NMR spectroscopic data and HRMS. Scoparic acid E (1) was tested for its effect on attenuating palmitate-induced viability at 25 and 50 μM. The results showed that compound 1 significantly attenuated palmitate-induced viability in MIN6 cells.