Anatolian Journal of Emergency Medicine
Yazarlar: Ziyaettin UZUN, Vahide Aslıhan DURAK, Halil İbrahim ÇIKRIKLAR, Melehat DİRİCAN, Cengiz BOZYİĞİT, Hilal MUTLU, Erol ARMAGAN
Konular:Tıp
Anahtar Kelimeler:Head trauma,Emergency Department,Ubiquitin C-Terminal Hydrolase-L1,Computed tomography
Özet: Aim: Head trauma is an important public health problem with high morbidity and mortality rates. In the pediatric age group, admissions to the emergency department with head trauma are high in our country as well as all over the world. Majority of these are minor head injuries. Our aim is to investigate whether Ubiquitin C-Terminal Hydrolase-L1 levels can be an alternative to computerized brain tomography in children who admitted to the emergency department due to minor head trauma. Material and Methods: Patients aged between 0 and 18 years who applied to Bursa Uludag University Medical Faculty Hospital Emergency Medicine Department in the first 6 hours due to minor head trauma between 07.03.2019 and 27.02.2020 were included in the study. Serum Ubiquitin C-Terminal Hydrolase-L1 blood levels were measured in patients who had computerized brain tomography. Results: 61 patients; 70.49% male (n = 43) and 29.51% (n = 18) female, and 20 volunteers as control group were included in the study. A statistically significant correlation was found between the positivity of computerized brain tomography (p <0.05). When the results of Ubiquitin C-Terminal Hydrolase-L1 were compared according to the groups, in the computerized brain tomography (+) group the mean value was 18,24 ng / ml, in the computerized brain tomography (-) group the mean value was 20,11 ng / ml and 8,93 ng / ml in the control group. A statistically significant difference was observed between the groups for the level of Ubiquitin C-Terminal Hydrolase-L1 (p <0.05). Conclusion: Ubiquitin C-Terminal Hydrolase-L1 level was higher in patients with minor head trauma compared to the control group. However, Ubiquitin C-Terminal Hydrolase-L1 levels were not found effective in showing the damage detected by computed brain tomography in children with minor head trauma.